Making our mark on cancer care
Metamark is leading a shift in urological cancer care to enable patients and their physicians to make more informed treatment decisions that lead to better quality of life and lower cost of care.
More informed treatment decisions improved patient outcomes
Addressing the complete diagnostic and therapeutic journey of a prostate cancer patient, Metamark offers deep urology expertise with unrivaled urology solutions through a complementary mix of traditional and world-class proprietary products, and best-in-class science published in top-tier scientific journals.
The Metamark Advantage
Sensitivity and Accuracy
In contrast to standard gene-based tests where the tissue sample is ground up and levels of individual genes in diseased tissue are diluted with normal tissue values, Metamark measures protein biomarkers in the regions of the intact tissue where they are altered during disease. This enables detection of even very small changes in a biomarker, and requires much less tissue to run the test than what is routinely required for genetics-based tests.
Objective, Automated Analyses
The Metamark platform does not rely on subjective interpretation of which regions of the tissue sample should be used for the biomaker measurements. The measurements are made in molecularly defined "regions-of-interest", and therefore are fully reproducible and objective.
Predicting Progression Risk at Early Disease Stage
Metamark can not only measure protein levels, but also protein activity states in intact tissues. In contrast to a majority of genetic alterations that usually occur in a fraction of patients with a particular disease and usually at later stages of disease, certain core proteins have deregulated activity at an early stage of disease and therefore are informative for virtually 100% of patients with a particular disease.
Metamark: Past, Present, and Future
Since its founding in 2007 by world leaders in cancer biology, molecular diagnostics and personalized medicine, Metamark has evolved into a trailblazer in clinical proteomics – the study of proteins and protein signatures within healthy and diseased cells. With the acquisition of HealthTronics Laboratory Solutions in 2013, a national provider of specialized anatomic and clinical uropathology testing services, Metamark became a leader in the diagnosis and management of prostate cancer, cancer of the bladder, and other urologic conditions.
Metamark believes that its advanced proteomics platform, together with its demonstrated expertise in biomarker identification, proteomics signature discovery, and clinical study design, will be applicable across multiple tumor types and other diseases where tissue is available. Metamark’s executive leadership team has industry-leading experience in discovering, validating and commercializing novel diagnostic and prognostic tests. With guidance from its world-class scientific and clinical advisors, and the support of a board of directors with extensive experience in building transformational life sciences companies, Metamark is leading a shift in urological cancer care, to a world in which patients and their physicians make more informed treatment decisions based on the latest proteomic science.